Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.
Ingcaciso yeMveliso
Ishishini lemichiza liyaqhubeka nokuguquka, liqhutywa yimfuneko yeekhompawundi ezintsha kwizicelo ezahlukeneyo.Sivuyiswa kakhulu ukwazisa i-4-cyano-2-methoxybenzaldehyde, i-compound enoluhlu olubanzi lokusetyenziswa.Le ngqungquthela inefomula ekhethekileyo ye-molecular C9H7NO2 kunye ne-molecular weight ye-161.16, kwaye inamandla amakhulu kumashishini amaninzi.
I-4-Cyano-2-methoxybenzaldehyde iyona nto ingundoqo kwaye inesakhiwo esizinzile nesichazwe kakuhle.Oku kuvula indlela yoluhlu olubanzi lwezicelo, ukusuka kumayeza ukuya kwimichiza yezolimo kunye nenzululwazi yemathiriyeli.Ulwakhiwo lwemolekyuli enamandla yale khompawundi, kudityaniswe neempawu zayo ezimangalisayo, ibambe amandla okuvelisa izinto ezintsha.
Enye yezona zinto ziqaphelekayo ze-4-cyano-2-methoxybenzaldehyde kukukwazi ukusebenza njengendawo ephakathi kwi-synthesis yeentlobo ezahlukeneyo ze-organic compounds.Ukuguquguquka kwayo kuvumela ukuveliswa kweendidi ezahlukeneyo, nganye ineempawu zayo ezizodwa kunye nokusetyenziswa.Kwiikhemisti kunye nabaphandi, oku kunika ithuba elingazange libonwe ngaphambili lokuphonononga iindawo ezintsha kunye nokuphuhlisa iikhompawundi zenoveli ezihlangabezana neemfuno ezithile.
Ngaphaya koko, ubunzima bemolekyuli yekhompawundi kunye nefomula iyenza isebenze njengesiseko sophuhliso lwamachiza.Ubukho bayo kwi-synthesis yeziyobisi kuphucula ukufumaneka kwe-bioavailability kwaye iququzelele ukuveliswa kwamachiza anamandla.Ngokunyibilika kwayo okugqwesileyo kuluhlu olubanzi lwezinyibilikisi, i-4-cyano-2-methoxybenzaldehyde iye yaba sisithako esiyimfuneko kushishino lwamayeza kukhangelo lwezisombululo ezitsha zonyango.
Kwintsimi ye-agrochemical, le khompawundi idlala indima ebalulekileyo njengenxalenye ebalulekileyo ekuphuhliseni amayeza okubulala izitshabalalisi kunye nemichiza yokutshabalalisa ukhula.Iimpawu zayo ezikhethekileyo, ezifana nokuzinza kunye nokusebenza kwakhona, vumela ukudala izisombululo ezisebenzayo zokukhusela izityalo.Abalimi kunye nabavelisi be-agrochemicals banokuthembela kwi-4-cyano-2-methoxybenzaldehyde ukwandisa ukusebenza kunye nokusebenza kakuhle kweemveliso zabo, ekugqibeleni kunceda ukwandisa isivuno kunye nokuveliswa kokutya.
![I-Tofacitinib ePhakathi 1,4-Chloro-7-p-toluenesulfonyl-7H pyrrolo [2,3-d] pyrimidine CAS No. 479633-63-1](http://cdn.globalso.com/jdkhc/1.14-Chloro-7-p-toluenesulfonyl-7H-pyrrolo-23-d-pyrimidine.jpg)
