Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.
Ingcaciso yeMveliso
I-compound, enenombolo ye-CAS ye-146464-90-6, i-compound efunwa kakhulu ngenxa yeempawu zayo ezintle kunye noluhlu olubanzi lwezicelo.Idityaniswe ngononophelo kusetyenziswa itekhnoloji yanamhlanje ukuqinisekisa ukucoceka kwayo kunye nokusebenza ngempumelelo kwiimvavanyo ezahlukeneyo zelabhoratri.Iinkqubo zokwenziwa ngobuchule ziqinisekisa umgangatho ophezulu wemveliso yokugqibela kwaye zihlangabezana neemfuno ezingqongqo zophando lwezenzululwazi.
Enye yezona zinto zinomdla kakhulu kule khompawundi kukusebenza kwayo okwahlukeneyo.Ulungelelwaniso lwalo lwemolekyuli luyenza ikwazi ukusebenzisana neentlobo ngeentlobo zeekhompawundi zezinto eziphilayo, iyenza ibe ngumgqatswa ogqwesileyo woluhlu olubanzi lwezicelo.Iimpawu zayo ezikhethekileyo zenza ukuba zilungele ukusetyenziswa njenge-reagent kuphando lwamachiza, i-organic synthesis kunye nohlalutyo lweekhemikhali.
Abaphandi kwinkalo ye-pharmacology baya kuzuza ngokukodwa kwiipropati ze-methyl 4- (methoxycarbonyl) -α-2-propargyl-phenylacetate.Isakhono sayo sokusebenzisana ngokukhethayo kunye neethagethi ezithile zebhayoloji ibambe isakhono esikhulu sokufunyanwa nophuhliso lwamachiza.Ngokusebenzisa le khompawundi, izazinzulu ziya kukwazi ukuyila amayeza atsha ajolise kwizifo ezithile ngokuchanekileyo nangempumelelo.
Kwintsimi ye-organic synthesis, le khompawundi inika amathuba angapheliyo.Ulwakhiwo lwayo olusebenzayo luvumela ukuveliswa kweemolekyuli ze-organic eziyinkimbinkimbi ngeendlela ezahlukeneyo zokuphendula imichiza.Iikhemisti ziya kuxabisa ukusebenza kakuhle kwayo ekwenzeni i-catalyzing reactions kunye nokukwazi kwayo ukwenza i-intermediates ezinzileyo, ukwenza lula iinkqubo zokwenziwa.
Ukongezelela, i-methyl 4- (methoxycarbonyl) yethu -α-2-propargyl-phenylacetate inozinzo oluhle kakhulu kunye nokuphila ixesha elide, evumela ukusetyenziswa kwexesha elide ngaphandle kokuphazamisa ingqibelelo yayo.Ukusebenza kwayo okuthembekileyo kuqinisekisa iziphumo ezingaguqukiyo nezinokuphinda zikwazi ukuveliswa, ukwandisa ukuthembeka kovavanyo kunye nokunciphisa inkunkuma enokubakho.
