Inkcazo
Inombolo ye-CAS 1378865-93-0, I-4-methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) yethu ye-pyridine yenziwe ngokucophelela kwaye ivavanywe ukuhlangabezana neyona migangatho iphezulu yokucoceka kunye nomgangatho.Idlala indima ebalulekileyo ekudityanisweni kwe-Alpelisib, unyango ekujoliswe kulo kwizigulana ezinomhlaza webele ophezulu okanye amathumba aqinileyo ane-PIK3CA utshintsho.
Le Alpelisib ephakathi isebenza njengebhloko yokwakha i-Alpelisib synthesis, eyenza ukuveliswa kwamachiza abonise ukusebenza okubonakalayo kwizilingo zeklinikhi.Ubume obuchanekileyo beekhemikhali zabaphakathi bethu buqinisekisa ukuhambelana kwabo kunye nokusebenza ngexesha lokudibanisa, ukufaka isandla ekucocekeni okuphezulu kunye namandla emveliso yokugqibela yamayeza.
I-4-Methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) i-pyridine ephakathi iyona nxalenye ephambili kwi-chemical synthesis ye-Alpelisib kunye neyona nto iphakathi kuyo yonke inkqubo yokuvelisa.Ngefomula yayo echanekileyo ye-molecular kunye nobunzima, yenzelwe ukuhlangabezana neemfuno ezingqongqo zokuvelisa amayeza, ukuqinisekisa ukuhambelana nokuthembeka kwimveliso ye-Alpelisib.
Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.
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