Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.
Ingcaciso yeMveliso
I-Ethyl 2-cyanoacetate yinxalenye yenkqubo yokuvelisa iyeza lonyango elisebenzayo kakhulu iFinerenone kwaye liphakathi eliphambili ekudibaneni kweli chiza lempumelelo.Eyaziwa ngokusebenza kwayo okugqwesileyo ekunyangeni isifo sezintso esingapheliyo kunye nokusilela kwentliziyo, iFinerenone ifumene ingqwalasela ebanzi kubasebenzi bezempilo kunye nezigulana.Ngoko ke, ukubaluleka kwe-ethyl 2-cyanoacetate ayikwazi ukugqithiswa njengoko idlala indima ebalulekileyo ekuveliseni eli chiza eliguqula ubomi.
Inombolo ye-CAS ye-ethyl 2-cyanoacetate yi-65193-87-5.Ineentlobo ngeentlobo zeepropathi eziluncedo eziyahlula kwezinye iindawo zamayeza.Isakhiwo sayo se-molekyuli sibonelela ngokuzinza okugqwesileyo kunye nokuhambelana neempendulo ezahlukeneyo zeekhemikhali, ukuqinisekisa inkqubo yokwenziwa komthungo.Ikhompawundi nayo inobunyulu obuphezulu, inyusa ngakumbi ukuthembeka kwayo kunye nokusebenza kakuhle.
Amaziko ethu okuvelisa aphucukileyo kunye namanyathelo okulawula umgangatho angqongqo aqinisekisa iimveliso ezikumgangatho ophezulu ezihlangabezana neyona migangatho ingqongqo yoshishino.Yonke ibhetshi ye-ethyl 2-cyanoacetate ivavanywa ngokungqongqo ukuqinisekisa ukucoceka kwayo, amandla kunye nokhuseleko.Siyakuqonda ukubaluleka okubalulekileyo kokubonelela ngeemveliso ezithembekileyo nezikhuselekileyo, ngakumbi kwishishini lamayeza apho ubomi bubalulekile.
Ukongeza ekusebenzeni kwayo okugqwesileyo njenge-finerenone ephakathi, i-ethyl 2-cyanoacetate ibonelela ngezinto ezininzi kwezinye izicelo.Iimpawu zayo ezikhethekileyo zeekhemikhali zenza ukuba ibe yinto ebalulekileyo ekuveliseni iintlobo ezahlukeneyo zamachiza kunye neekhemikhali ezintle.I-Ethyl 2-cyanoacetate inoluhlu olubanzi lwezinto ezinokuthi zisetyenziswe, inikezela ngamathuba amaninzi okuvelisa izinto ezintsha kunye nokuqhubela phambili kwi-chemistry yamayeza.
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