Inkcazo
I-Vorolazan ePhakathi ye-5 yinxalenye ephambili kwi-synthesis ye-Vorolazan, iklasi ye-compounds enamandla yamachiza eyaziwayo ngemiphumo yabo yokwelapha.Esi siphakathi sidlala indima ephambili kwimveliso yeVorolazan, esetyenziselwa ukuphuhliswa kwezonyango ezahlukeneyo zonyango.
Isakhiwo se-molecular ye-Vorolazan Intermediate 5 ineqela le-2-fluorophenyl eqhotyoshelwe kwi-pyrrole-3-carboxaldehyde moiety, inika iipropati ezizodwa zeekhemikhali ezenza ukuba zibaluleke kakhulu kuphando lweziyobisi kunye nophuhliso.Isakhiwo sayo sobunjineli ngononophelo sivumela ukuguqulwa ngokuchanekileyo kunye nokuguqulwa, okwenza kube yinto ebalulekileyo kwimveliso yeVolorazan.
Inombolo ye-CAS 881674-56-2 sisichongi esikhethekileyo sale khompawundi ephakathi, iqinisekisa ukulandeleka kwayo kunye nokuqinisekiswa komgangatho kwizicelo ezahlukeneyo zamayeza.Oku kuqinisekisa ukuthembeka kunye nokuhambelana kweVorolazan Intermediate 5 kuphando lwamachiza, uphuhliso kunye nokuvelisa.
Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.